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5-Fluoroorotic acid (5-FOA)
Cat. No. Size Price Description
HAA12-5 5g  
HAA12-10 10g  
HAA12-25 25g  
 
Description
CAS Number: 703-95-7
 
5-Fluoroorotic acid (5-FOA)

MOLECULAR BIOLOGY GRADE

C5H3FN2O4

MW:174.09 g/mol

White to slightly off white crystalline powder

5-Fluoroorotic Acid (5-FOA) is widely used in the field of yeast molecular genetics. 5-FOAs toxicity to yeast cells with a functioning URA3 gene, which encodes orotidine-5-P decarboxylase (OMP decarboxylase), makes it especially useful for the selection and identification of mutant yeast strains. 5-FOA is most often applied with Saccharmoyces cerevisiae (URA3), although it has been used in other strains including Schizosaccharmoyces pombe (URA4 and URA5), Candida albicans (URA3) and the bacterium E. coli (pyrF). 5-FOAs use in the yeast 2-hybrid system allows for the construction of activation domain hybrid libraries to identify protein-protein interactions.

Store at -15C and protect from light.

PubChem Chemical ID: 69711